Back in the misty Days of Yore (it was mid-summer 2006), I published a series of articles on this very website that looked at the all time top 25 in each of five major counting categories. The idea was to assess the chances of some active players of cracking those lists. The categories were: a) Runs, b) RBIs, c) Hits, d) HRs.
I was also going to do pitcher wins and strikeouts, but I ran out of gas after wins and never made it to strikeouts. It would be interesting to carry out the same exercise today, but there's a fair bit of work involved and we'll just have to see how willing I am to do it.