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Week 16 NFL Picks: Tips for Vegas Odds and over-Under Score Predictions

The penultimate week of the 2019-20 NFL season will feature several clashes with major playoff implications, including Buffalo's trip to AFC East rivals New England and Dallas' visit to Philadelphia in the NFC East.

Miami and Cincinnati will go head-to-head in a battle of the teams with the worst records in the AFC, and Green Bay visits Minnesota with the NFC North on the line.

Here's a look at the full matchup list, complete with spread odds, the over-under and picks (all odds courtesy of Caesars):

Matchup, Spread, Over-Under, Pick

Houston at Tampa Bay, HOU -3, 50.