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Week 14 NFL Picks: Latest Betting Odds, Vegas Spreads and Projections

The New Orleans Saints can become the front-runner for NFC home-field advantage in Week 14.

With a home win over San Francisco 49ers, Sean Payton's team would have wins over both NFC West teams in contention for the No. 1 seed. The NFC South champion is 5-1 inside the Superdome.

San Francisco's last two road contests have been decided by three points and it is 1-2 in its last three clashes with playoff teams.

Over in the AFC, the Baltimore Ravens are in control of the No. 1 seed after the New England Patriots lost in Week 13.