Villanova has a chance to become the first team since 1999 to sweep all of the Big East titles over a two-year span.
Stopping that dominance would give Seton Hall a conference tournament championship for the first time in 23 years.
The third-ranked Wildcats look to beat the Pirates for the third time this season Saturday night at Madison Square Garden and head into the NCAA Tournament as a No. 1 seed with major momentum.
Villanova (29-4) has already won the last two regular-season conference championships, and can now make it two straight tournament titles. It would become the first Big East team to take all four in consecutive seasons since Connecticut in 1998-99.