The 2016 NFL season was the first in modern league history in which a left-handed quarterback did not throw a single pass.
Sure, quarterbacks occasionally improvise by throwing the ball with their wrong hand, and Dallas Cowboys wide receiver Dez Bryant threw a left-handed touchdown pass off a reverse against the Detroit Lions in December. But Cowboys backup Kellen Moore was the only active left-handed signal-caller in the NFL last year, and he continues to be today. Moore spent the entire 2016 campaign on injured reserve while recovering from a fractured fibula in his right leg.