The Seattle Seahawks placed two key offensive players, wide receiver Tyler Lockett and running back Alex Collins, on the reserve/COVID-19 list on Thursday.
The roster moves come just three days before the Seahawks face the NFC West rival Los Angeles Rams on the road.
Seattle's playoff hopes are hanging by a thread, as it is currently last in the NFC West with a 5-8 record, but the team enters Sunday's contest on a two-game winning streak.
Of the two potential absences, Lockett will likely hurt the most since he is Seattle's leading receiver this season.