The Indianapolis Colts already had a difficult backfield to read and things have only gotten more confusing with Marlon Mack ruled out of Sunday's matchup against the New England Patriots with a hamstring injury.
With the versatile second-year player unavailable, the Colts will likely turn to a few different players to help pick up the slack in the backfield. While this depth is valuable for the team remaining competitive going forward, it's tricky impossible for fantasy football owners to predict.
Indianapolis drafted two running backs last spring and both Nyheim Hines and Jordan Wilkins figure to be important parts of the offense for the rest of the season.