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Penn State vs. Indiana College Football Odds, Plays and Insights

Sep 25, 2021; University Park, Pennsylvania, USA; Penn State Nittany Lions head coach James Franklin rings the victory bell following the completion of the game against the Villanova Wildcats at Beaver Stadium. Penn State defeated Villanova 38-17. Mandatory Credit: Matthew OHaren-USA TODAY Sports

Big Ten rivals meet when the No. 4 Penn State Nittany Lions (4-0, 0-0 Big Ten) host the Indiana Hoosiers (2-2, 0-0 Big Ten) on Saturday, October 2, 2021 at Beaver Stadium. Penn State is favored by 12.5 points. The over/under is set at 53.5.

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