The Panthers are 13-0 and closing in on the fifth perfect regular season in N.F.L. history, while quarterback Cam Newton makes a strong case for the Most Valuable Player Award.
The Giants are 6-7, have shown a habit of throwing games away late, and are alive in the playoff chase only because they are lucky enough to play in the pitiful N.F.C. East.
So when the teams play Sunday, it seems like a mismatch is in the cards. What would we expect the opening betting line to be on the game?