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NFL Predictions Week 4: Top Underdogs Picks, Vegas Odds and Score Predictions

Don't expect the NFL's Week 4 offering to cough up as many lucrative upsets as the week prior.

Upsets will still occur, of course, but there is likely zero chance the Week 4 slate can match the magnitude of say, Buffalo overcoming an opening spread of 17 points to beat Minnesota. Or Washington taking down Green Bay. Or Detroit trouncing New England.

Call last week the dream scenario for those who love the thrill of rolling with an underdog and the payoff that comes with it. This week, then, is the return to reality—a handful of upsets will happen, though they won't be as obvious as something such as going against a 17-point spread, like we advised to do.