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NFL Predictions Week 1: Picks and Projections for Top Upsets on the Schedule

With much of the United States off work Monday for Labor Day and football making its triumphant return on Thursday, this week is one to be celebrated. While time seemed to stretch on agonizingly after the New England Patriots and St. Louis Rams took their last snaps in Super Bowl LIII, our long nightmare is finally over.

The new season brings tidings of joy, intrigue and drama. It's no coincidence that most of the matchups we've pegged as upset specials in the projections below involve a team with a new head coach, a new quarterback, or, if you're the Arizona Cardinals, both!