Two division titles and one wild-card spot are on the line in Week 18's Sunday games.
The NFC South will be decided in the early-afternoon window, while the NFC North and No. 1 overall seed in the NFC will be determined on Sunday night.
The final wild-card spot yet to be clinched comes from the AFC, where the Denver Broncos hold all the power.
Denver must beat the Kansas City Chiefs to qualify for the postseason. A loss eliminates the Broncos because the Cincinnati Bengals defeated the Pittsburgh Steelers on Saturday night.
Cincinnati still needs Denver and the Miami Dolphins to lose to get in, but at least it still has a chance to qualify on the final day of the regular season.