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March Madness betting: North Carolina vs. UCLA highlight Friday's Sweet 16 picks

The NCAA tournament is officially wide open.

Three No. 1 seeds are out after Arizona and Gonzaga went down on Thursday. Baylor bowed out in the second round. That leaves Kansas as the lone top seed left in March Madness.

Kansas takes the court in Sweet 16 action on Friday night. Here are the picks for Friday's games, with the spreads from BetMGM:

Ochai Agbaji of the Kansas Jayhawks leads his team into March Madness' Sweet 16. (Photo by Tom Pennington/Getty Images)
Ochai Agbaji of the Kansas Jayhawks leads his team into March Madness' Sweet 16. (Photo by Tom Pennington/Getty Images)

Purdue (-12.5) over St. Peter's

Miami is the second-lowest rated KenPom Sweet 16 team, at No.