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Kentucky vs Tennessee Prediction: Odds, Expert Picks, Betting Trends and Stats for 2025 March Madness

For the third time this season, the Kentucky Wildcats (24-11) will take the court Friday to play the Tennessee Volunteers (29-7).

Kentucky won the two regular season games. Are those two meetings a factor to consider as the teams prepare for Round 3? The stakes for this matchup are substantially higher than in either of those first two meetings. This time they meet in the Sweet 16 in Indianapolis.

Under first-year head coach and former Wildcat Mark Pope, Kentucky has exceeded expectations. Kentucky is the first school in the history of the NCAA Tournament to reach the Sweet 16 without one player on the roster who scored in the previous season.