It is too early to know some Week 6 injury designations for certain, but it is not too early to start ironing out your lineup decisions. You'll need to continue monitoring the health of players such as Alvin Kamara, David Johnson, Tyreek Hill and Marquise Brown, but positional rankings can help decide your starters.
For 12-team, non-points-per-reception leagues that award four points per passing touchdown, we'll rank the likely starters at each position (top 12 for quarterbacks and tight ends, top 24 for running backs and receivers) and dive into a few of the more surprising ranks.
Week 6 Rankings
Top 12 Quarterbacks
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