The Philadelphia Eagles announced that running back Miles Sanders was ruled out for the remainder of Sunday's matchup against the New York Giants with a hand injury.
Sanders also missed time earlier this season with an ankle injury he suffered in a Week 7 loss to the Las Vegas Raiders. He missed three games while on injured reserve with that ailment. He returned for a Week 11 win over the New Orleans Saints.
Losing Sanders for any period of time isn't good for the Eagles, who rank toward the top of the NFL in rushing yards.