There are no NFL byes in Week 13, which means all healthy players will be available for your daily fantasy needs. This is great for flexibility, but it doesn't necessarily make setting your ideal lineups any easier. More top players will be draftable, but this only makes picking the very best of the best that much more difficult.
It also makes it harder to sort out the top value picks with which to round out your rosters.
In either case, there are two basic strategies that tend to pay off in DFS in weeks like this.