Fantasy managers and player proposition bettors find Week 5 of the NFL season kicking off with a Thursday Night matchup between the Colts and Broncos.
Both teams are dealing with major issues at the running back position. The Broncos lost leading rusher Javonte Williams (ACL, LCL) for the season last week, while Indianapolis is uncertain if star tailback Jonathan Taylor (ankle) will be healthy enough to suit up on the short week.
Michael Pittman, Courtland Sutton and Jerry Jeudy will be starting in almost every fantasy league.