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College football scores, games, updates: Marshall at Ohio State, NC State at Clemson and more

Week 4 of the college football season features the start of conference play for many teams, and it includes two games between teams ranked in the top 15. Both of those matchups could prove to be crucial at the end of the season.

Here are the biggest games left on Saturday.

(All times are Eastern and all odds are from BetMGM.)

No. 11 USC at No. 18 Michigan

Time: 3:30 p.m. | TV: CBS | Line: USC -6 | Total: 44.