Cam Newton threw for 422 yards and two touchdowns in his NFL debut. For good measure, he added a one-yard rushing touchdown that gave his Panthers a third-quarter lead. He wound up and strummed the ball like a guitar in the end zone and pantomimed pulling open his shirt in his famous Superman celebration, though his Panthers would fall to the Cardinals 28–21. But the headlines came from that eye-popping three-digit number: The much-hyped Auburn product, the Heisman Trophy winner and No. 1 pick in the 2011 draft, was the first quarterback ever to throw for more than 400 yards in his NFL debut.