The Arizona Cardinals own the edge in the recent rivalry with the Los Angeles Rams, winning five of the last seven meetings outright, going 5-2 against the spread.
Freshly energized Arizona hopes to extend that run when it takes on Los Angeles on Sunday across the pond at Twickenham Stadium in London.
NFL point spread: The Rams opened as 2.5-point favorites; the total was 47.5 early in the week, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
NFL betting pick, via OddsShark computer: 30.8-15.2 Rams (NFL picks on every game)
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