As much as we obsess over how NFL teams look on paper before the season, Super Bowl runs can come down to who stays healthiest over the course of a long, arduous season. The 2017 Eagles are the obvious counter-example, given that they won with Carson Wentz, Jason Peters and others sidelined, but they're a rare exception to what has generally been a rule. We're also seeing those same Eagles struggle under the weight of a new set of injuries this season.
Of course, even the healthiest NFL team is going to put up with injuries here and there.