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2025 NFL Draft betting, odds, lines: Shedeur Sanders to the Saints? Oddsmakers think so

Shedeur Sanders opened as the +300 favorite at BetMGM to be drafted No. 1 overall last year, and while that ship has likely sailed — Sanders is currently 66-1 to be drafted first in the 2025 NFL Draft, which starts April 24, while Cam Ward is -10000 — Sanders remains the biggest liability in that market at sportsbooks.

A more interesting question revolves around which team will draft Sanders, and potentially if Jaxson Dart passes him as the second quarterback selected. The QB position is always one of supply and demand in the league, and the number of open positions is lower than usual as the draft approaches — although free agent Aaron Rodgers' decision looms large as well.