Running back handcuffs -- you either love 'em or hate 'em. Regardless, you need to know who the "next-man-up" is for every team. It might be the best way to find a fantasy football sleeper, and it should be part of your draft strategy and in-season waiver wire pickup strategy.
Of course, RB handcuffs are subject to change on a moment's notice, which is why we'll be updating this list all season long. It's important to note that many teams don't have a true "starter" and "handcuff", instead going with a committee approach. Also, there are players whose roles might be unchanged even when a starter gets hurt (Dion Lewis, Duke Johnson Jr.