Traded Clint Brannon to the Chicago Cubs for Jon Leicester.
December 8, 2005
Traded Alfonso Soriano to the Washington Nationals for Brad Wilkerson, Armando Galarraga, and Terrmel Sledge.
Traded Esteban German to the Kansas City Royals for Rule 5 selection Fabio Castro.
December 12, 2005
Traded a player to be named later (Ricardo Rodriguez) to the Philadelphia Phillies for Vicente Padilla.
January 6, 2006
Traded Adrian Gonzalez, Chris Young, and Terrmel Sledge to the San Diego Padres for Adam Eaton, Akinori Otsuka, and Billy Killian.
March 31, 2006
Traded Juan Dominguez to the Oakland Athletics for John Rheinecker and (as part of three-team trade) John Koronka and cash from the Chicago Cubs.