Estonia's Anett Kontaveit became the highest seed to be knocked out of Wimbledon so far as she was beaten in straight sets by German Jule Niemeier.
"Amazing. I am speechless to be honest," said the 22-year-old Niemeier after reaching the third round.
Kontaveit has spoken about suffering from the longer-term effects of Covid recently and arrived at SW19 having not played since the French Open in May.
Niemeier added: "It is one of the biggest wins of my career so far.
"Winning at Wimbledon on Court One is an amazing feeling. I am happy I could handle the situation today.