Britain's number two Heather Watson fought back against American Nicole Gibbs at the French Open before play was suspended because of rain.
But Gibbs had the upper hand and was serving at 7-5 2-6 2-1 when the players were called off on Sunday evening.
Watson dropped her serve twice as she went down in the first set, but bounced back after the first rain delay.
The 24-year-old comfortably took the second set but her serve was broken early in the third.
Fellow Briton Kyle Edmund was among a host of players scheduled to begin their campaigns on day one but who must now wait on the weather.