American great Serena Williams' impending farewell to the court will understandably grab most of the attention when an intriguing US Open packed with storylines begins on Monday.
British teenager Emma Raducanu's defence of the women's singles is another fascinating proposition, while British men's number one Cameron Norrie tries to back up his run to the Wimbledon semi-finals with another strong run at a major.
Spain's Rafael Nadal has only played once since pulling out of Wimbledon through injury but has the chance to extend his men's singles record of 22 major titles with nearest rival Novak Djokovic not allowed to play.