Serena Williams will play Montenegro's Danka Kovinic in the US Open first round as she begins what is set to be the final tournament of her career.
Britain's Emma Raducanu starts the defence of the women's singles title against France's Alize Cornet.
Raducanu, seeded 11th, returns to Flushing Meadows where she won last year as an 18-year-old qualifier.
More to follow.