Holding the US Open without fans was "not an easy" decision but the "correct one", says the United States Tennis Association.
The USTA has confirmed the Grand Slam event will be held behind closed doors in New York from 31 August, despite some top players voicing concerns.
"We are confident we have a plan that is safe, viable, and the right thing to do for our sport," the USTA said.
The ATP and WTA Tours, suspended since March, will resume in early August.
There have been no professional tennis events in the past three months because of the coronavirus pandemic.