Last year's US Open runner-up Daniil Medvedev cruised past world number 138 JJ Wolf in straight sets to reach the fourth round.
The Russian third seed beat the American 21-year-old 6-3 6-3 6-2 and is yet to drop a set at this year's tournament.
Medvedev, 24, will play either American Frances Tiafoe or Hungary's Marton Fucsovics next.
"It's good that I managed to win in three sets," he said.
"With six months of not playing tennis it's not easy to recover from four or five-set matches."
Fellow Russian Andrey Rublev, 22, is also through to the fourth round after the 10th seed beat Italy's Salvatore Caruso 6-0 6-4 6-0.