Johanna Konta believes playing on Arthur Ashe Stadium can inspire her to beat fifth seed Elina Svitolina and reach the US Open semi-finals.
The British 16th seed meets Ukrainian Svitolina on the world's biggest tennis court at 17:00 BST on Tuesday.
Konta, 28, has reached the quarter-finals in three successive majors.
"I'm lucky to have played on all the Grand Slam centre courts and it is another opportunity to play on one," she said.
"Ashe is a big court, it is a bit quicker than the other courts and I'm really looking forward to it.