Williams, who had not competed in singles on tour since withdrawing from Wimbledon last year with an injury, lost in three sets to Harmony Tan of France.
WIMBLEDON, England — It was the 21st time that Serena Williams has played Wimbledon. It was Harmony Tan’s first time, but Tan will be the player heading to the second round at the All England Club.
Tan, a Frenchwoman ranked 115th who is little-known even in her country, defeated Williams, the greatest women’s tennis champion of her era, 7-5, 1-6, 7-6 (10-7).