Qualifier Lulu Sun's dream run to the Wimbledon quarter-finals was ended by Croatian Donna Vekic under the roof on Court One.
New Zealander Sun, 23, who beat Britain's Emma Raducanu in the fourth round, was hoping to become the first qualifier to reach the women's semi-finals since 1999 when American Alexandra Stevenson caused a sensation.
However, the world number 123 was beaten 5-7 6-4 6-1 by Vekic who will face Jasmine Paolini or Emma Navarro in the last four.
World number 37 Vekic, at the age of 28, is into her first Grand Slam semi-final.