Roger Federer finally cracked under the serve of John Isner, losing, 7-6 (3), 3-6, 7-6 (5), in the third round of the Paris Masters. Isner will next face eighth-seeded David Ferrer.
Earlier, Novak Djokovic extended his winning streak to 19 matches and advanced to the quarterfinals by beating 14th-seeded Gilles Simon, 6-3, 7-5. Djokovic will next face No. 5 Tomas Berdych, who beat No. 9 Jo-Wilfried Tsonga, 6-3, 6-4.
Rafael Nadal, seeded seventh, almost followed Federer through the exit door, saving a match point in a 4-6, 7-6 (6), 6-2 win against 11th-seeded Kevin Anderson.