British women's number one Katie Boulter was knocked out of the US Open second round in a "horrendous" defeat by Jessica Bouzas Maneiro, while Jack Draper claimed a straightforward win against Argentina's Facundo Diaz Acosta.
Boulter, the 31st seed, started strongly in the opening set, but ultimately fell to a 7-5 7-5 loss against Spain's Bouzas Maneiro, ranked 74th.
British men's number one Draper, meanwhile, moved seamlessly into the third round with a 6-4 6-2 6-2 success.
He could face Spain's Carlos Alcaraz if the French Open and Wimbledon champion defeats Dutchman Botic van de Zandschulp in Thursday's evening session on Arthur Ashe Stadium.