Defending champion Naomi Osaka is out of the Australian Open after American opponent Amanda Anisimova survived two match points before clinching a memorable third-round victory.
Unseeded Anisimova, 20, will play Australian top seed Ashleigh Barty in the last 16.
Barty has still not dropped a set this week after a 6-2 6-3 victory over Italy's Camila Giorgi.
More to follow.