A record crowd was on hand at Amon G. Carter Stadium to watch the TCU football team kick off the 2023 season against the Colorado Buffaloes and new head coach Deion Sanders. In what became a track meet during the second half, TCU and Colorado combined for over 1,000 yards of total offense in the contest, but it was the Buffaloes who ultimately emerged victorious, stunning the Horned Frogs 45-42 and handing the defending national championship runner-ups a season-opening defeat.
TCU entered as three-touchdown favorites, but the Horned Frog defense was nonexistent throughout the day, as the Buffaloes saw four wide receivers eclipse 100 yards and quarterback Shedeur Sanders throw for 510 yards and four touchdowns.