The United States lost its World Cup qualifying match 1-0 to hosts Panama for its first defeat of the campaign to reach the 2022 tournament in Qatar.
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A header from a corner kick in th 54th minute by Anibal Godoy that grazed off USMNT striker Gyasi Zardes and into the net was the sole goal at Estadio Rommel Fernandez.
The U.S. seemed out of sorts against a spirited Panamanian side all evening, producing very little scoring opportunities against the Central American side.