Sunderland Women will play a minimum of four of their Championship matches at the Stadium of Light next season.
The Black Cats finished third in the league last season, five points adrift of champions Crystal Palace.
The other 18 league matches will be played at their regular home, the Eppleton Colliery Welfare Ground.
“With the evolution of the women’s game and the current developments to the ground, we are delighted that we will be hosting games at the Stadium of Light, said SAFC women’s general manager Alex Clark.
"It provides exciting opportunities for our players and allows us to further connect with the city.