John O'Shea is at home in Ireland after the death of his father, having also missed the defeat to Leicester.
Victor Anichebe is pushing for a recall but on-loan winger Adnan Januzaj is ineligible to face his parent club.
Antonio Valencia will return at right-back after being rested, with Paul Pogba also likely to start.
Ashley Young is out after picking up a knock against Everton and Wayne Rooney is also sidelined with an ankle injury.
MOTD COMMENTATOR'S NOTES
Guy Mowbray: "In response to criticism of his Stoke side, then-manager Alan Durban was misquoted as once saying: 'If you want entertainment, go to a circus' (He may actually have said 'watch a bunch of clowns').