Manchester City's £47.5m signing John Stones could make his debut in defence, with Vincent Kompany unlikely to be fit because of a thigh problem.
New manager Pep Guardiola may also be without Leroy Sane (hamstring), while Kevin De Bruyne lacks fitness after an extended break following Euro 2016.
Sunderland forward Jermain Defoe is fit after a thigh strain for David Moyes' first game in charge.
New signings Papy Djilobodji, Donald Love and Paddy McNair could feature.
Billy Jones, Jan Kirchhoff and Sebastian Larsson are all slight doubts.
MOTD COMMENTATOR'S NOTES
Steve Wilson: "News that Manchester City's long courtship of Pep Guardiola was finally to succeed broke last February - the day before Manuel Pellegrini's side won 1-0 at Sam Allardyce's Sunderland.