Sunderland and Peterborough United were among 14 clubs to reach the last 32 of the EFL Trophy on Tuesday.
The Black Cats beat Carlisle 5-3, while Posh overcame Fulham Under-21s 4-2.
Fleetwood qualified from the same group as Sunderland as Harvey Saunders scored a hat-trick inside the first 15 minutes of their 3-0 win over Aston Villa U21s.
Elsewhere, Norwich U21s also progressed from the group stage as Tyrese Omotoye netted three times in their 5-0 victory at Newport County.
Portsmouth's win at Southend was enough to seal a spot in the knock-out round for Pompey and West Ham U21s, despite the Hammers not being in action.