Joe Allen will miss Stoke's trip to Manchester City due to the concussion he suffered while on international duty with Wales.
The 27-year-old midfielder took a blow to the head having been caught between David Meyler and James McClean during the Republic of Ireland's victory in Cardiff on Monday that dashed Wales' World Cup hopes.
Hughes revealed Allen had little recollection of the incident and would be missing at the Etihad Stadium because he was not far enough along in the concussion protocol process.
"Joe's not great; we've given him a couple of days just to stay at home," Hughes said.