Stoke City will expand its first-team training facilities and renovate its current provision for its academy and women's team in a major £12m project.
Work is expected to begin at Clayton Wood training ground in September after planning permission was granted by Newcastle-under-Lyme Borough Council.
The new building will increase the "scale and quality" of facilities available to players, the Championship club said.
The work is the biggest financial outlay on a single project since the building of the bet365 Stadium in 1997, a spokesperson said.
"The new state-of-the art building will create elite facilities for the men’s first team squad and will in turn lead to a renovated version of the existing pavilion being provided exclusively to the club’s category one academy and women’s team," the club said.