Manchester City manager Pep Guardiola awaits news on whether captain Vincent Kompany will be fit enough to play.
He remains without long-term injury victims Gabriel Jesus and Ilkay Gundogan.
Stoke's Xherdan Shaqiri is available after missing five matches with a calf problem.
However, Marko Arnautovic, Glen Johnson and Bruno Martins Indi are doubtful, while Wilfried Bony is ineligible to play against his parent club.
WHAT THE MANAGERS SAY
Manchester City Pep Guardiola: "It's a pity that the distance between Chelsea [and Manchester City] is so big, but that's true. We started the season with 10 games winning, but our game was not like today.