Cincinnati struck first, getting back-to-back homers from Joey Votto and Adam Duvall with two outs in the first. Votto's opposite-field blast into the Reds bullpen, came just one after the Cardinals got an umpire's call overturned that resulted in Jose Peraza being ruled out with a caught stealing at third base. On the next pitch, Votto connected for his 27th homer of the season.
It was the team-leading 32nd long ball of 2016 for Duvall.
At the start of the second inning, Michael Wacha replaced Jaime Garcia.
MATHENY SHUFFLES CARDS LINEUP; CARPENTER OUT
The Cardinals and Reds square off at 7:15 p.