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The Cardinals had been held to one run or none 12 times this season while ace right-hander Miles Mikolas had been on the mound.
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- St. Louis native Ross Detwiler becomes the 450th player Pujols has homered against, breaking the mark held by Barry Bonds.
- Pujols homers off the 449th pitcher he's faced in his career, tying Barry Bonds for the most all-time.