Yadier Molina got the game's first run, blasting a home run off the front of the third deck in left field to give the Cardinals a 1-0 lead on the Giants after four innings.
It was Molina's third home run of the season and his first in almost two months. His most recent came on June 19 against Philadelphia. It was the 99th career home run for Molina. It came on a 1-2 pitch from Giants pitcher Chris Heston and was estimated at 403 feet.
After Stephen Piscotty flew out to right, Heston walked Brandon Moss and Mark Reynolds.