After an off day Thursday, the best-of-five series resumes with Game 3 on Friday in San Diego.
The wild-card Padres beat the rival Dodgers for the first time in a postseason game. San Diego was swept 3-0 by the Dodgers in a 2020 Division Series and lost Game 1 of this series Tuesday.
Dropped from first to seventh in the batting order for matchup purposes, Profar grounded a single to right field in the sixth off reliever Brusdar Graterol, who took the loss. Jake Cronenworth scored for a 4-3 lead.
Cronenworth homered off Blake Treinen in the eighth to give San Diego some insurance, and Josh Hader earned his first four-out save since August 2020 with Milwaukee.